INT22897

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Context Info
Confidence 0.49
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Tmprss11d) extracellular region (Tmprss11d) plasma membrane (Tmprss11d)
Tmprss11d (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 5 99.34 Very High Very High Very High
opiate 4 98.44 Very High Very High Very High
Abstinence syndrome 4 97.30 Very High Very High Very High
Dextromethorphan 6 94.94 High High
antagonist 1 94.76 High High
ketamine 2 75.00 Quite High
Morphine 1 71.40 Quite High
Physical dependence 1 56.20 Quite High
Disease Link Frequency Relevance Heat
Syndrome 4 97.30 Very High Very High Very High
Drug Dependence 1 56.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As ASP and GLU antagonists K and DM have this antagonizing effect on the precipitated abstinence syndrome signs, the manifestation of abstinence syndrome may mainly result from the normalization of ASP and GLU production because of the disinhibition by NL of the enzymes and the stronger stimulation of ASPergic/GLUergic receptors which have no opiate blockade after NL injection.
Positive_regulation (stimulation) of ASP associated with syndrome, antagonist, narcan, dextromethorphan, opiate and abstinence syndrome
1) Confidence 0.49 Published 1990 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 2345761 Disease Relevance 0.40 Pain Relevance 1.07

General Comments

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