INT228984

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Context Info
Confidence 0.63
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CRP, IL6) extracellular region (CRP, IL6) aging (IL6)
CRP (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 32 93.68 High High
cytokine 38 60.64 Quite High
Inflammatory marker 7 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 86 97.88 Very High Very High Very High
INFLAMMATION 42 93.68 High High
Death 9 62.24 Quite High
Myocardial Infarction 7 61.84 Quite High
Nicotine Addiction 5 25.00 Low Low
Atherosclerosis 4 25.00 Low Low
Injury 3 25.00 Low Low
Atherosclerotic Plaque 3 25.00 Low Low
Hypertension 1 25.00 Low Low
Overweight 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, our findings suggest that CRP may stimulate IL-6.
CRP Spec (may) Positive_regulation (stimulate) of IL-6
1) Confidence 0.63 Published 2008 Journal Archives of Drug Information Section Body Doc Link PMC2817441 Disease Relevance 0.17 Pain Relevance 0.11
Ignoring this variability, we found an odds ratio for CHD, adjusted for several established risk factors, of 1.46 (95% CI 1.29–1.65) per 2 standard deviation (SD) increase of baseline IL-6 values, similar to that for baseline C-reactive protein.
C-reactive protein Positive_regulation (increase) of IL-6 associated with coronary heart disease
2) Confidence 0.17 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2288623 Disease Relevance 0.82 Pain Relevance 0.05

General Comments

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