INT229098

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.47
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (TP53) nucleoplasm (TP53) mitochondrion (TP53)
endoplasmic reticulum (TP53) enzyme binding (TP53) protein complex assembly (TP53)
Anatomy Link Frequency
smooth muscle cell 1
TP53 (Homo sapiens)
IER3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 68.56 Quite High
headache 2 33.88 Quite Low
Central nervous system 10 18.40 Low Low
Inflammation 8 11.56 Low Low
Angina 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Paresthesia 1 5.00 Very Low Very Low Very Low
dysesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 104 100.00 Very High Very High Very High
Apoptosis 1 97.08 Very High Very High Very High
Infection 71 92.00 High High
Adhesions 1 88.84 High High
Hematological Disease 3 85.20 High High
Thrombosis 9 59.76 Quite High
Congenital Anomalies 3 58.16 Quite High
Myelodysplastic Syndromes 1 53.04 Quite High
Disease 12 44.16 Quite Low
Convulsion 2 40.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, one of the immediate-early gene products of CMV, namely IE84, binds to p53 and inhibits its transcriptional activity, thus inhibiting p53-mediated apoptosis, and enhancing vascular smooth muscle cell proliferation [4].
p53 Binding (binds) of immediate-early in smooth muscle cell associated with cytomegalovirus infection and apoptosis
1) Confidence 0.01 Published 2008 Journal Virol J Section Body Doc Link PMC2289809 Disease Relevance 1.47 Pain Relevance 0.03

General Comments

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