INT229105

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LMOD1) cytoskeleton (LMOD1) plasma membrane (GRIN1)
cytoplasm (LMOD1)
Anatomy Link Frequency
pyramidal neurons 1
GRIN1 (Homo sapiens)
LMOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 3 100.00 Very High Very High Very High
Dopamine 80 99.32 Very High Very High Very High
Pyramidal cell 12 98.18 Very High Very High Very High
agonist 14 95.54 Very High Very High Very High
Nucleus accumbens 6 52.28 Quite High
Eae 1 47.96 Quite Low
positron emission tomography 4 21.80 Low Low
Catechol-O-methyltransferase 17 5.00 Very Low Very Low Very Low
Thalamus 4 5.00 Very Low Very Low Very Low
Clonidine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 17 87.08 High High
Attention Deficit Hyperactivity Disorder 36 58.16 Quite High
Stress 4 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Hyperkinesis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low
Hypotension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Application of the D1 receptor agonist SKF81297 has been shown to cause a prominent increase of steady-state NMDA-evoked current in acutely isolated PFC pyramidal neurons, and up-regulation of NMDA receptor activity by dopamine D1 receptors suggests reciprocal interactions between D1 and NMDA receptors [65].
NMDA Binding (interactions) of D1 in pyramidal neurons associated with dopamine, nmda receptor, pyramidal cell and agonist
1) Confidence 0.07 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2289834 Disease Relevance 0.15 Pain Relevance 0.40

General Comments

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