INT229132

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 0.83
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rem1) GTPase activity (Rem1) cellular_component (Rem1)
biological_process (Rem1)
Anatomy Link Frequency
neurons 2
Rem1 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 10 66.56 Quite High
medulla 28 56.00 Quite High
Locus ceruleus 40 38.24 Quite Low
Raphe 4 37.32 Quite Low
gABA 64 13.36 Low Low
amygdala 16 8.40 Low Low
withdrawal 18 5.00 Very Low Very Low Very Low
monoamine 14 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
Neuropeptide 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 60 75.60 Quite High
Unconsciousness 22 73.64 Quite High
Sleep Disorders 170 60.72 Quite High
Targeted Disruption 60 54.00 Quite High
Vibrio Infection 8 40.40 Quite Low
Overdose 16 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 8 5.00 Very Low Very Low Very Low
Depression 8 5.00 Very Low Very Low Very Low
Sarcoma 4 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was a result of an increase in the number of short (<1.3 minutes) bouts of REM sleep (F1, 13?
Negative_regulation (bouts) of Gene_expression (sleep) of REM
1) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709920 Disease Relevance 0 Pain Relevance 0
There was a significant correlation between loss of the GFP neurons and REM sleep (r?
Negative_regulation (loss) of Gene_expression (sleep) of REM in neurons
2) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709920 Disease Relevance 0.22 Pain Relevance 0
In the lesioned mice, the average length of REM sleep bouts did not change at night compared to HCRT-ko mice given saline, but the average length of the non-REM (F1, 26?
Negative_regulation (length) of Gene_expression (bouts) of REM
3) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709920 Disease Relevance 0.12 Pain Relevance 0
As with lesions in the HCRT-ko mice vlPAG lesions produced a significant increase in the number of REM bouts (F1, 14?
Negative_regulation (number) of Gene_expression (bouts) of REM
4) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709920 Disease Relevance 0.35 Pain Relevance 0
Individual states and their transitions resembled the REM/nREM cycle of natural sleep in their EEG components, evolution, and time frame (?
Negative_regulation (resembled) of Gene_expression (cycle) of nREM
5) Confidence 0.10 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2289875 Disease Relevance 0.07 Pain Relevance 0.06
Individual states and their transitions resembled the REM/nREM cycle of natural sleep in their EEG components, evolution, and time frame (?
Negative_regulation (resembled) of Gene_expression (cycle) of REM
6) Confidence 0.10 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2289875 Disease Relevance 0.07 Pain Relevance 0.06

General Comments

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