INT229152

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Abcg1) transport (Abcg1) Golgi apparatus (Abcg1)
ATPase activity (Abcg1) plasma membrane (Abcg1) intracellular (Abcg1)
Anatomy Link Frequency
Macrophages 1
Abcg1 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 11 77.36 Quite High
interneuron 7 76.56 Quite High
agonist 15 36.00 Quite Low
imagery 19 5.00 Very Low Very Low Very Low
Pyramidal cell 14 5.00 Very Low Very Low Very Low
alcohol 11 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 288 99.32 Very High Very High Very High
Targeted Disruption 16 90.24 High High
Atherosclerosis 49 83.12 Quite High
Atherosclerotic Plaque 3 74.96 Quite High
Hypolipidemia 2 45.76 Quite Low
Insulin Resistance 2 42.96 Quite Low
Metabolic Syndrome 1 40.80 Quite Low
Coronary Heart Disease 33 5.00 Very Low Very Low Very Low
Myocardial Infarction 19 5.00 Very Low Very Low Very Low
Cardiovascular Disease 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HDL (Kennedy et al 2005) Macrophages deficient in ABCG1 also have impaired FC efflux and accumulate excess cholesterol (Out R 2006).
Negative_regulation (deficient) of ABCG1 in Macrophages associated with disorder of lipid metabolism
1) Confidence 0.19 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.35 Pain Relevance 0
We engineered adeno-associated viruses (AAVs) that express GFP, dsRedExpress, or channelrhodopsin (ChR2) upon Cre/loxP recombination-mediated removal of a transcription-translation STOP cassette.
Negative_regulation (removal) of cassette
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2289876 Disease Relevance 0 Pain Relevance 0.08

General Comments

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