INT229203

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Bcl2, Cyp2c11) mitochondrion (Bcl2) aging (Bcl2)
cell morphogenesis (Bcl2) intracellular (Bcl2) response to stress (Bcl2)
Anatomy Link Frequency
neurons 1
Bcl2 (Rattus norvegicus)
Cyp2c11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 10 96.20 Very High Very High Very High
Inflammation 2 94.92 High High
cytokine 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 11 100.00 Very High Very High Very High
Apoptosis 1 100.00 Very High Very High Very High
Cv General 4 Under Development 5 96.56 Very High Very High Very High
INFLAMMATION 3 94.92 High High
Lymphatic System Cancer 2 93.88 High High
Leukemia 2 93.52 High High
Stress 2 80.88 Quite High
Stroke 27 74.96 Quite High
Convulsion 1 70.76 Quite High
Brain Hemorrhage 8 49.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bcl2 protects neurons against ischemic injury via its anti-apoptotic activity (Kitagawa 2007; Mattson 2007), and CYP2C11 metabolizes arachidonic acid to expoxyeicosatrienoic acids, which are thought to protect against cerebral ischemia via vasodilatory, anti-inflammatory and antioxidant activities (Koerner and Alkayed 2007).
Bcl2 Binding (metabolizes) of CYP2C11 in neurons associated with inflammation, cv general 4 under development, ischemia, injury and apoptosis
1) Confidence 0.36 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2291013 Disease Relevance 1.20 Pain Relevance 0.17

General Comments

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