INT229204

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2) aging (Bcl2) cell morphogenesis (Bcl2)
endoplasmic reticulum (Bcl2) intracellular (Bcl2) response to stress (Bcl2)
Anatomy Link Frequency
cortex 2
Olr1254 (Rattus norvegicus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 10 54.88 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Middle Cerebral Artery Infarction 14 63.68 Quite High
Toxicity 2 57.24 Quite High
Cv General 4 Under Development 5 55.60 Quite High
Stroke 27 50.00 Quite Low
Injury 11 5.00 Very Low Very Low Very Low
Brain Hemorrhage 8 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the PND50 brain, A1254 at 0.1 mg/kg/day reduced Bcl2 expression in the female cortex (Figure 5B), whereas both A1254 doses increased Bcl2 in the male cortex (Figure 5D).
A1254 Negative_regulation (reduced) of Gene_expression (expression) of Bcl2 in cortex
1) Confidence 0.02 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2291013 Disease Relevance 0.18 Pain Relevance 0.03

General Comments

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