INT229217

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.72
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F8) oxidoreductase activity (F8) extracellular region (F8)
cell adhesion (F8) plasma membrane (F8)
Anatomy Link Frequency
platelets 2
F8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 2 52.12 Quite High
tolerance 7 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 90 100.00 Very High Very High Very High
Injury 8 95.96 Very High Very High Very High
Hemorrhage 46 72.28 Quite High
Reprotox - General 1 1 15.76 Low Low
Toxicity 1 7.20 Low Low
Disease 7 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 5 5.00 Very Low Very Low Very Low
Factor Viii Deficiency 4 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Accordingly, expression of FVIII in platelets was shown to be effective at inducing hemostasis even when FVIII protein expression levels did not exceed 1% of normal levels.
Regulation (effective) of Gene_expression (expression) of FVIII in platelets
1) Confidence 0.41 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2939703 Disease Relevance 0.55 Pain Relevance 0
Subjects with severe or moderately severe hemophilia A (baseline FVIII level ?
Regulation (Subjects) of Gene_expression (level) of FVIII associated with coagulation disorder
2) Confidence 0.39 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291300 Disease Relevance 0.17 Pain Relevance 0.03

General Comments

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