INT229243

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 2.32
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (BAX) cytosol (BAX) mitochondrion (BAX)
endoplasmic reticulum (BAX) nucleus (BAX) cytoplasm (BAX)
BAX (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 10 68.84 Quite High
ischemia 110 53.84 Quite High
Angina 40 5.00 Very Low Very Low Very Low
adenocard 30 5.00 Very Low Very Low Very Low
Kinase C 15 5.00 Very Low Very Low Very Low
bradykinin 15 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Opioid 10 5.00 Very Low Very Low Very Low
Catecholamine 10 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 280 99.32 Very High Very High Very High
Death 60 79.44 Quite High
Pressure And Volume Under Development 10 70.56 Quite High
Pain 10 68.84 Quite High
Cv Unclassified Under Development 105 53.84 Quite High
Necrosis 40 50.00 Quite Low
Myocardial Infarction 55 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 35 5.00 Very Low Very Low Very Low
Reperfusion Injury 25 5.00 Very Low Very Low Very Low
Infarction 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have shown that pharmacological activation of these kinases is associated with recruitment of anti-apoptotic signaling components such as the phosphorylation and inhibition of the proapoptotic proteins Bax and Bad, the inhibition of caspase 3 activation, the phosphorylation and activation of p70S6K (which acts to inhibit Bad) and the phosphorylation and activation of the antiapoptotic protein Bcl-2 (Harada et al 2001; Hausenloy and Yellon 2007).
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of Bax associated with apoptosis
1) Confidence 0.18 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291307 Disease Relevance 0.48 Pain Relevance 0.10
Recent studies have shown that pharmacological activation of these kinases is associated with recruitment of anti-apoptotic signaling components such as the phosphorylation and inhibition of the proapoptotic proteins Bax and Bad, the inhibition of caspase 3 activation, the phosphorylation and activation of p70S6K (which acts to inhibit Bad) and the phosphorylation and activation of the antiapoptotic protein Bcl-2 (Harada et al 2001; Hausenloy and Yellon 2007).
Negative_regulation (inhibit) of Phosphorylation (phosphorylation) of Bax associated with apoptosis
2) Confidence 0.18 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291307 Disease Relevance 0.44 Pain Relevance 0.09
Recent studies have shown that pharmacological activation of these kinases is associated with recruitment of anti-apoptotic signaling components such as the phosphorylation and inhibition of the proapoptotic proteins Bax and Bad, the inhibition of caspase 3 activation, the phosphorylation and activation of p70S6K (which acts to inhibit Bad) and the phosphorylation and activation of the antiapoptotic protein Bcl-2 (Harada et al 2001; Hausenloy and Yellon 2007).
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of Bax associated with apoptosis
3) Confidence 0.18 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291307 Disease Relevance 0.43 Pain Relevance 0.09
Recent studies have shown that pharmacological activation of these kinases is associated with recruitment of anti-apoptotic signaling components such as the phosphorylation and inhibition of the proapoptotic proteins Bax and Bad, the inhibition of caspase 3 activation, the phosphorylation and activation of p70S6K (which acts to inhibit Bad) and the phosphorylation and activation of the antiapoptotic protein Bcl-2 (Harada et al 2001; Hausenloy and Yellon 2007).
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of Bax associated with apoptosis
4) Confidence 0.18 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291307 Disease Relevance 0.48 Pain Relevance 0.10
Recent studies have shown that pharmacological activation of these kinases is associated with recruitment of anti-apoptotic signaling components such as the phosphorylation and inhibition of the proapoptotic proteins Bax and Bad, the inhibition of caspase 3 activation, the phosphorylation and activation of p70S6K (which acts to inhibit Bad) and the phosphorylation and activation of the antiapoptotic protein Bcl-2 (Harada et al 2001; Hausenloy and Yellon 2007).
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of Bax associated with apoptosis
5) Confidence 0.18 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291307 Disease Relevance 0.49 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox