INT229292

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.14
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (FXR1) extracellular region (FGF19) nucleolus (FXR1)
RNA binding (FXR1) nucleus (FXR1) cytoplasm (FXR1)
Anatomy Link Frequency
fibroblast 4
FXR1 (Homo sapiens)
FGF19 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 117 90.32 High High
Cholecystokinin 3 38.52 Quite Low
agonist 6 5.00 Very Low Very Low Very Low
nud 6 5.00 Very Low Very Low Very Low
Migraine 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Sumatriptan 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 18 94.88 High High
Diabetes Mellitus 87 92.72 High High
Body Weight 3 90.32 High High
Coronary Artery Disease 75 50.00 Quite Low
Atherosclerosis 39 50.00 Quite Low
Obesity 9 23.76 Low Low
Disorder Of Lipid Metabolism 69 5.00 Very Low Very Low Very Low
Hyperlipidemia 15 5.00 Very Low Very Low Very Low
Gallstones 9 5.00 Very Low Very Low Very Low
Hyperglycemia 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, FXR positively regulates expression of fibroblast growth factor 19 (FGF19).
FXR Regulation (regulates) of Gene_expression (expression) of fibroblast growth factor 19 in fibroblast
1) Confidence 0.08 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291317 Disease Relevance 0.37 Pain Relevance 0.16
Similarly, FXR positively regulates expression of fibroblast growth factor 19 (FGF19).
FXR Regulation (regulates) of Gene_expression (expression) of FGF19 in fibroblast
2) Confidence 0.06 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291317 Disease Relevance 0.38 Pain Relevance 0.16
Therefore, the administration of BAS would be expected to decrease the FXR-regulated expression of FGF19, with potential increases in glucose levels.
FXR Regulation (regulated) of Gene_expression (expression) of FGF19
3) Confidence 0.04 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291317 Disease Relevance 0.39 Pain Relevance 0.04

General Comments

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