INT229330

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GCK) small molecule metabolic process (GCK) carbohydrate metabolic process (GCK)
DNA binding (Nr1h2) transmembrane transport (GCK) cytoplasm (Nr1h2)
Nr1h2 (Mus musculus)
GCK (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 39 81.88 Quite High
agonist 2 53.44 Quite High
nud 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
Sumatriptan 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 1 93.36 High High
Insulin Resistance 1 92.40 High High
Repression 6 90.56 High High
Hyperglycemia 3 71.92 Quite High
Metabolic Disorder 1 57.92 Quite High
Obesity 3 52.84 Quite High
Coronary Artery Disease 25 50.00 Quite Low
Atherosclerosis 13 50.00 Quite Low
Disorder Of Lipid Metabolism 23 48.64 Quite Low
Diabetes Mellitus 29 42.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, increased LXR activity downregulates 11 beta-hydroxysteroid dehydrogenase type 1 (Stulnig et al 2002), downregules PPAR gamma, coactivator-1 alpha, and gluconeogenic enzymes such as PEPCK and glucose-6-phosphatase (Cao et al 2003; Laffitte et al 2003) and increases expression of glucokinase and GLUT-4 (Laffitte et al 2003).
LXR Binding (activity) of Positive_regulation (increases) of Gene_expression (expression) of glucokinase
1) Confidence 0.01 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291317 Disease Relevance 0.62 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox