INT229360

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Context Info
Confidence 0.48
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Agt, Agtr1a) endosome (Agtr1a) extracellular space (Agt)
extracellular region (Agt) Golgi apparatus (Agtr1a) plasma membrane (Agtr1a)
Agt (Rattus norvegicus)
Agtr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 1 96.32 Very High Very High Very High
Angina 1 85.92 High High
Catecholamine 5 65.12 Quite High
antagonist 6 58.16 Quite High
bradykinin 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 48 99.12 Very High Very High Very High
Stroke 1 87.16 High High
Cv General 3 Under Development 1 85.92 High High
Atherosclerosis 1 83.32 Quite High
Pressure And Volume Under Development 1 70.92 Quite High
Exanthema 1 67.92 Quite High
Cough 3 67.68 Quite High
Pituitary Cancer 1 66.56 Quite High
Targeted Disruption 1 59.80 Quite High
Hypertension 2 59.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although we can not rule out the possibility that Ang IV may directly activate the AT1 receptor with a dosage of exogenous Ang IV in the micromolar range, our binding studies with Sarile did not support the interpretation of such a non-specific binding of Ang IV to the AT1 receptor.
Ang IV Positive_regulation (activate) of AT1 receptor
1) Confidence 0.48 Published 2007 Journal The open cardiovascular medicine journal Section Body Doc Link PMC2570565 Disease Relevance 0.35 Pain Relevance 0.08
Angiotensin II mediates its activity via the AT1 receptor, which is selectively blocked by ARBs.
Angiotensin II Positive_regulation (mediates) of AT1 receptor
2) Confidence 0.24 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291334 Disease Relevance 0.90 Pain Relevance 0.12

General Comments

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