INT229371

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pparg, Edn1) enzyme binding (Pparg) DNA binding (Pparg)
cell-cell signaling (Edn1) cytosol (Pparg) signal transduction (Pparg)
Anatomy Link Frequency
endothelial cells 3
Pparg (Rattus norvegicus)
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 79.00 Quite High
tolerance 18 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 11 97.04 Very High Very High Very High
Disorder Of Lipid Metabolism 15 87.12 High High
Atherosclerosis 1 86.72 High High
Disease 3 85.44 High High
Insulin Resistance 27 79.88 Quite High
INFLAMMATION 2 78.60 Quite High
Diabetes Mellitus 55 78.56 Quite High
Metabolic Syndrome 7 61.04 Quite High
Impaired Glucose Tolerance 18 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In cultured endothelial cells ligand activation of PPAR gamma has been shown to inhibit thrombin-induced endothelin-1 production (Delerive et al 1999) and plasminogen activator inhibitor type 1 expression (Kato et al 1999).
Positive_regulation (activation) of PPAR gamma in endothelial cells Negative_regulation (inhibit) of Gene_expression (production) of endothelin-1 in endothelial cells
1) Confidence 0.01 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291335 Disease Relevance 0.92 Pain Relevance 0.04

General Comments

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