INT229392

Context Info Confidence 0.20 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 2.18 Pain Relevance 0.32

mitochondrion (MPO) extracellular space (MPO) oxidoreductase activity (MPO) aging (MPO) nucleus (MPO) lysosome (MPO)

MPO (Homo sapiens)

Pain Link Frequency Relevance Heat ischemia 26 99.56 Parenteral administration 1 87.56 Inflammatory response 1 79.40 methotrexate 16 72.96 cytokine 5 34.56 withdrawal 1 16.24 antagonist 8 5.00 Infliximab 6 5.00 Inflammation 6 5.00 Etanercept 5 5.00

Disease Link Frequency Relevance Heat Urological Neuroanatomy 22 100.00 Cv Unclassified Under Development 24 99.56 Injury 60 91.80 Adhesions 6 88.12 Adverse Drug Reaction 1 86.48 Hepatotoxicity 2 80.00 INFLAMMATION 6 79.04 Pneumonia 1 78.60 Mucositis 1 78.08 Disease 42 71.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A recent small open-label study in China compared MMF and CYP for induction of remission in 35 patients, mainly MPO-positive, with serum creatinine <500 ?

Negative_regulation (compared) of Positive_regulation (induction) of MPO associated with urological neuroanatomy

1) Confidence 0.20 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2893757 Disease Relevance 0.80 Pain Relevance 0.19

The increased mucosal MPO activity after reperfusion can be significantly attenuated by the use of antioxidants.

Negative_regulation (attenuated) of Positive_regulation (increased) of MPO associated with urological neuroanatomy

2) Confidence 0.14 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2291499 Disease Relevance 1.38 Pain Relevance 0.12

General Comments

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