INT229401

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (FUT3) Golgi apparatus (FUT3)
Anatomy Link Frequency
LES 2
FUT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 52 80.56 Quite High
Neuropeptide 5 23.28 Low Low
cytokine 20 14.40 Low Low
Bile 7 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
substance P 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acid Reflux 18 96.84 Very High Very High Very High
Adenocarcinoma 6 82.68 Quite High
INFLAMMATION 46 80.56 Quite High
Stress 20 78.24 Quite High
Metaplasia 4 72.60 Quite High
Esophageal Disease 20 61.20 Quite High
Mucositis 6 49.84 Quite Low
Hypersensitivity 2 20.72 Low Low
Neurogenic Inflammation 2 17.20 Low Low
Dyspepsia 24 10.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cheng et al. reported that in a cat model of hydrochloric acid reflux, hydrogen peroxide was induced by an increase of IL-1 in the LES, after which it inhibited the release of acetylcholine from cholinergic nerve terminals and caused LES relaxation by stimulating the synthesis of prostaglandin (PG) E2 and platelet-activating factor (PAF) [31, 32].
Positive_regulation (caused) of Localization (relaxation) of LES in LES associated with acid reflux
1) Confidence 0.04 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2291500 Disease Relevance 0.81 Pain Relevance 0.07

General Comments

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