INT229426

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.06
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cat) mitochondrion (Cat) aging (Cat)
Golgi apparatus (Cat) endoplasmic reticulum (Cat) plasma membrane (Cat)
Anatomy Link Frequency
neutrophils 2
Cat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 20 59.04 Quite High
antagonist 1 49.92 Quite Low
imagery 1 35.64 Quite Low
Bioavailability 7 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 61 97.12 Very High Very High Very High
Increased Venous Pressure Under Development 74 94.32 High High
Urological Neuroanatomy 32 89.00 High High
Gallstones 13 74.56 Quite High
Stress 39 66.56 Quite High
INFLAMMATION 27 59.04 Quite High
Diabetes Mellitus 76 50.00 Quite Low
Body Weight 40 29.36 Quite Low
Disorder Of Lipid Metabolism 11 5.00 Very Low Very Low Very Low
Obesity 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vascular reactivity in the presence of the hydrogen peroxide scavenger catalase (1200 U/mL) or an inhibitor of cyclooxygenase (COX) (indomethacin, 10 ?
Negative_regulation (reactivity) of Localization (presence) of catalase
1) Confidence 0.32 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2887873 Disease Relevance 0.29 Pain Relevance 0
Therefore, it seems likely that the enhanced decreases in hepatic SOD and GSSG-R activities and the decrease in hepatic catalase, Se-GSHpx, and G-6-PDH activities found at a progressed stage of liver injury in ANIT-treated rats are due to ROS derived from neutrophils accumulating in the tissue.
Negative_regulation (decreases) of Localization (decrease) of catalase in neutrophils associated with injury
2) Confidence 0.28 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2291502 Disease Relevance 0.76 Pain Relevance 0.03
One unit of catalase is defined as the amount of enzyme, which decomposes 1??
Negative_regulation (defined) of Localization (unit) of catalase
3) Confidence 0.23 Published 2010 Journal Experimental Diabetes Research Section Body Doc Link PMC3014714 Disease Relevance 0 Pain Relevance 0

General Comments

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