INT22945

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 1984
Last Reported 2008
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.56
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Pdia3) endoplasmic reticulum (Pdia3)
Anatomy Link Frequency
liver 1
Pdia3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 5 100.00 Very High Very High Very High
anesthesia 2 66.44 Quite High
Rheumatism 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Poisoning 1 91.20 High High
Diabetes Mellitus 37 90.44 High High
Hepatotoxicity 3 79.36 Quite High
Body Weight 2 11.56 Low Low
Stress 3 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Sexually Transmitted Diseases 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Crystal Associated Disease 1 5.00 Very Low Very Low Very Low
Rheumatic Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As screened in a few groups, the changes in microsomal NADPH cytochrome c reductase were not noteworthy.
Regulation (changes) of microsomal
1) Confidence 0.26 Published 1990 Journal Res. Commun. Chem. Pathol. Pharmacol. Section Abstract Doc Link 2353131 Disease Relevance 0 Pain Relevance 0.07
Microsomal UDP-glucuronosyltransferase activities towards a third group of substrates (including oestrone, phenolphthalein, paracetamol and oxazepam) are not markedly altered by treatment with either 3-methylcholanthrene or phenobarbital.
Neg (not) Regulation (altered) of Microsomal associated with paracetamol
2) Confidence 0.26 Published 1984 Journal Biochem. Pharmacol. Section Abstract Doc Link 6422942 Disease Relevance 0 Pain Relevance 0.10
The effect of H. indicus aqueous extract on the microsomal protein concentration and cytochrome P-450-dependent monooxygenase enzyme is given in Table 3.
Regulation (effect) of microsomal protein
3) Confidence 0.07 Published 2008 Journal International Journal of Diabetes in Developing Countries Section Body Doc Link PMC2772005 Disease Relevance 0.32 Pain Relevance 0
Guaiazulene administered to rats did not produce any macroscopic toxic effect and caused no change of liver weight, microsomal protein and total cytochrome P450 content.
Neg (no) Regulation (change) of microsomal protein in liver
4) Confidence 0.02 Published 1997 Journal Arch. Pharm. (Weinheim) Section Abstract Doc Link 9112807 Disease Relevance 0.25 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox