INT229459

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ndel1) transport (Ndel1) nuclear envelope (Ndel1)
chromosome segregation (Ndel1) chromosome (Ndel1) cytoskeleton (Ndel1)
Anatomy Link Frequency
nerves 2
Ndel1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 38 90.48 High High
Sciatic nerve 62 88.48 High High
Spinal cord 20 5.00 Very Low Very Low Very Low
butorphanol 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Dorsal column 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 44 90.48 High High
Embryonic Lethality 4 87.04 High High
Injury 42 76.80 Quite High
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, the Ndel1 siRNA reduced by 50% the levels of Ndel1 protein indicated by western blots (Fig. 6C and D).
Negative_regulation (reduced) of Gene_expression (levels) of Ndel1 protein
1) Confidence 0.41 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.24 Pain Relevance 0.03
Local silencing of Ndel1 by siRNA in injured nerves reduces axon regeneration
Negative_regulation (reduces) of Gene_expression (silencing) of Ndel1 in nerves
2) Confidence 0.40 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.52 Pain Relevance 0.26

General Comments

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