INT229501

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Nefl, Vim) cytosol (Vim) cytoskeleton (Vim)
locomotion (Nefl) cytoplasm (Vim)
Anatomy Link Frequency
neuronal 1
Nefl (Mus musculus)
Vim (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 38 94.56 High High
Sciatic nerve 62 75.04 Quite High
Spinal cord 20 5.00 Very Low Very Low Very Low
butorphanol 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Dorsal column 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 44 94.56 High High
Injury 42 83.48 Quite High
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Embryonic Lethality 4 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In tissues with higher regenerative capacity, Ndel1 preferentially associates with the neuronal form of Vimentin in detriment of NF-L.
NF-L Binding (associates) of Vimentin in neuronal
1) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.24 Pain Relevance 0.05
Based on this knowledge, we reasoned that upon axotomy, Ndel1 will interact less with NF-L (in favor of Vimentin) in tissues with higher regenerative potential.
NF-L Binding (interact) of Vimentin
2) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

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