INT229538

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Prnp) endoplasmic reticulum (Prnp) nucleolus (Prnp)
proteinaceous extracellular matrix (Cpz) plasma membrane (Prnp) nucleus (Prnp)
Anatomy Link Frequency
neurons 2
Cpz (Mus musculus)
Prnp (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 1 67.84 Quite High
medulla 1 67.20 Quite High
agonist 10 5.00 Very Low Very Low Very Low
Clonidine 5 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Scrapie 9 97.48 Very High Very High Very High
Sprains And Strains 10 97.16 Very High Very High Very High
Hypertension 6 95.12 Very High Very High Very High
Creutzfeldt Jakob Disease 4 83.48 Quite High
Disease 17 74.16 Quite High
Targeted Disruption 3 31.32 Quite Low
Infection 5 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover CPZ was not able to prevent PrPSc accumulation in primary cultures of tg338 mouse neurons infected with 127S scrapie strain [39].
CPZ Negative_regulation (prevent) of Positive_regulation (accumulation) of PrPSc in neurons associated with scrapie and sprains and strains
1) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291559 Disease Relevance 0.58 Pain Relevance 0.07

General Comments

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