INT229558

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Ctla4) plasma membrane (Ctla4)
Anatomy Link Frequency
T lymphocytes 2
Ctla4 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 65.00 Quite High
Analgesic 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 159 98.80 Very High Very High Very High
Glioma 9 91.60 High High
Brain Tumor 11 66.00 Quite High
Immunotherapy Of Cancer 1 50.00 Quite Low
Glioblastoma 26 12.84 Low Low
Residual Neoplasm 3 12.48 Low Low
Recurrence 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Fibromyalgia 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It remains to be investigated, however, whether CTLA4 depletion might also interfere with the clonal expansion of tumor-antigen specific T lymphocytes.
Spec (might) Negative_regulation (interfere) of Negative_regulation (depletion) of CTLA4 in T lymphocytes associated with cancer
1) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291560 Disease Relevance 0.48 Pain Relevance 0.03

General Comments

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