INT229652

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.88
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Myog) nucleus (Myog) DNA binding (Myog)
Anatomy Link Frequency
skeletal muscle 3
muscle 1
Myog (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 75.84 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Dysuria 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 6 92.20 High High
Targeted Disruption 21 87.84 High High
Cancer 23 86.96 High High
Embryonal Rhabdomyosarcoma 1 81.00 Quite High
INFLAMMATION 10 75.84 Quite High
Carcinoma 5 73.52 Quite High
Confusion 1 65.36 Quite High
Leiomyosarcoma 7 36.68 Quite Low
Rhabdomyosarcoma 2 29.12 Quite Low
Necrosis 5 6.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Myogenin is a basic helix-loop-helix (bHLH) transcription factor that is required for skeletal muscle differentiation [14], and therefore expression of the Cre gene under the control of the myogenin promoter allows for deletion of a gene of interest specifically in skeletal muscle [13].
Regulation (control) of myogenin promoter in skeletal muscle
1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0.17 Pain Relevance 0
In the same analysis, genes that encode proteins in contractile apparatus (Myh3 and Myl3), signaling and transcriptional regulation (Hif3, Camkk2, Myog and Ppara), metabolism (Bdh1 and Acsl1), neuromuscular junction (Chrng) and humoral regulation (Fgf4 and Il1b) along with many other genes are now confirmed to be controlled by the p38 MAPK pathway in skeletal muscle.
Regulation (regulation) of Myog in skeletal muscle
2) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0 Pain Relevance 0
In the same analysis, genes that encode proteins in contractile apparatus (Myh3 and Myl3), signaling and transcriptional regulation (Hif3, Camkk2, Myog and Ppara), metabolism (Bdh1 and Acsl1), neuromuscular junction (Chrng) and humoral regulation (Fgf4 and Il1b) along with many other genes are now confirmed to be controlled by the p38 MAPK pathway in skeletal muscle.
Regulation (regulation) of Myog in skeletal muscle
3) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0 Pain Relevance 0
Immunohistochemically, it has become apparent that h-caldesmon, myogenin and ALK-1, in contrast to muscle specific and smooth muscle actins, desmin and cytokeratin, can be of great value in the differential diagnosis of vesical IMTs [4,14,20].
Regulation (value) of myogenin in muscle
4) Confidence 0.03 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2292680 Disease Relevance 0.71 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox