INT229681

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Plec) plasma membrane (Plec) cytoskeleton (Plec)
cytoplasm (Plec)
Anatomy Link Frequency
lung 1
Plec (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 67 99.40 Very High Very High Very High
anesthesia 2 87.20 High High
isoflurane 3 85.60 High High
fibrosis 1 61.28 Quite High
Inflammation 19 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Loss 21 100.00 Very High Very High Very High
Adenocarcinoma 99 99.60 Very High Very High Very High
Shock 10 94.76 High High
Viral Infection 16 92.32 High High
Immunization 4 84.08 Quite High
Influenza Virus Infection 60 79.28 Quite High
Infection 80 78.28 Quite High
Severe Acute Respiratory Syndrome 14 67.92 Quite High
Metaplasia 6 62.56 Quite High
Fibrosis 1 61.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Development of Plectin-1 Targeted PDAC Imaging Agents
Negative_regulation (Development) of Plectin-1 associated with adenocarcinoma and imagery
1) Confidence 0.39 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2292750 Disease Relevance 0.69 Pain Relevance 0.17
The lack of any lung damage associated with the PCN treatment was further supported by the absence of any increase in the levels of serum albumin (Figure 3C) and lactate dehydrogenase (Figure 3D) recovered in the BALF of these mice at this time and the absence of any weight loss during the PCN treatment regimen (data not shown).
Negative_regulation (loss) of PCN in lung associated with weight loss
2) Confidence 0.20 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.45 Pain Relevance 0
The purified PCN was then stored at ?
Negative_regulation (stored) of PCN
3) Confidence 0.20 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.57 Pain Relevance 0.13

General Comments

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