INT229696

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rxrg)
Rxrg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 63 98.88 Very High Very High Very High
depression 74 50.00 Quite Low
Dopamine 10 12.84 Low Low
Serotonin 15 12.32 Low Low
Inflammation 76 5.00 Very Low Very Low Very Low
ischemia 50 5.00 Very Low Very Low Very Low
cytokine 17 5.00 Very Low Very Low Very Low
antidepressant 13 5.00 Very Low Very Low Very Low
Glutamate 8 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 50 84.68 Quite High
Diabetes Mellitus 22 60.72 Quite High
Obesity 5 59.68 Quite High
Post-partum Depression 30 50.00 Quite Low
Depression 59 16.84 Low Low
INFLAMMATION 89 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 46 5.00 Very Low Very Low Very Low
Stress 43 5.00 Very Low Very Low Very Low
Death 40 5.00 Very Low Very Low Very Low
Frailty 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both RXR and PPAR are composed of a ligand
Gene_expression (composed) of RXR
1) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2293414 Disease Relevance 0.08 Pain Relevance 0.07
 :RXR complex can recruit corepressor complexes
Gene_expression (can) of RXR
2) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2293414 Disease Relevance 0.18 Pain Relevance 0.08
In addition, LC-PUFAs are agonists at nuclear receptors, such as the retinoid X receptor (RXR) and peroxisome proliferator-activated receptors (PPAR), which modulate gene expression [27, 28].
Gene_expression (expression) of RXR associated with agonist
3) Confidence 0.04 Published 2011 Journal Depression Research and Treatment Section Body Doc Link PMC2989696 Disease Relevance 0 Pain Relevance 0.05

General Comments

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