INT229790

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (AGXT) small molecule metabolic process (AGXT) peroxisome (AGXT)
cellular nitrogen compound metabolic process (AGXT)
AGXT (Homo sapiens)
Pain Link Frequency Relevance Heat
Hsan 94 83.48 Quite High
Pain 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
unmyelinated 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
lancinating pain 1 5.00 Very Low Very Low Very Low
syringomyelia 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
diabetic neuropathy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 94.96 High High
Peripheral Neuropathy 1 86.64 High High
Hereditary Sensory And Autonomic Neuropathies 101 83.48 Quite High
Neuropathic Pain 13 53.24 Quite High
Disease 24 5.00 Very Low Very Low Very Low
Syndrome 7 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Charcot Marie Tooth Disease 6 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low
Cough 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of sphingolipid synthesis at the SPT step prevents a harmful accumulation of metabolic sphingolipid-intermediates including sphingoid bases and ceramide, whereas repression of other anabolic steps in the spingolipid synthetic pathway may cause intermediates to accumulate.
Regulation (Regulation) of Gene_expression (synthesis) of SPT associated with repression
1) Confidence 0.11 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2311280 Disease Relevance 0.47 Pain Relevance 0.24

General Comments

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