INT229971

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Context Info
Confidence 0.68
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.91
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (C1S) extracellular region (C1S)
Anatomy Link Frequency
pneumocytes 1
bile 1
C1S (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 16 100.00 Very High Very High Very High
Inflammation 52 98.88 Very High Very High Very High
fibrosis 33 77.80 Quite High
Inflammatory response 2 50.72 Quite High
beta blocker 1 22.68 Low Low
corticosteroid 1 18.64 Low Low
alcohol 5 12.84 Low Low
cva 8 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 150 100.00 Very High Very High Very High
INFLAMMATION 52 98.88 Very High Very High Very High
Infection 12 97.56 Very High Very High Very High
Respiratory Syncytial Virus 1 97.16 Very High Very High Very High
Adult Respiratory Distress Syndrome 5 94.84 High High
Lung Injury 4 93.28 High High
Cardiovascular Disease 16 89.56 High High
Pneumonia 14 88.88 High High
Pneumocystis Carinii Infection 2 85.84 High High
Dyslipidemia /

Combined Dyslipidemia

15 85.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP-C is exclusively synthesized by alveolar type II pneumocytes and secreted into the alveolar space [19].
Localization (secreted) of SP-C is in pneumocytes
1) Confidence 0.68 Published 2008 Journal BMC Pulm Med Section Body Doc Link PMC2364613 Disease Relevance 1.49 Pain Relevance 0.16
As the name suggests, the reverse cholesterol transport process involves the transport of HDL-C from peripheral tissues and transfer to VLDL-C and LDL-C back to liver for secretion in the bile.9 HDL-C is also believed to have anti-inflammatory, anti-oxidative, platelet anti-aggregatory, anticoagulation, and profibrolytic effects,13 which can help reduce damage mediated by high levels of LDL-C.
Localization (secretion) of C is in bile associated with bile, inflammation and disorder of lipid metabolism
2) Confidence 0.68 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 1.33 Pain Relevance 0.12
It also prevents spontaneous activation of C1 and binding to the zymogen forms of C1r and C1s [24].
Localization (forms) of C1s
3) Confidence 0.09 Published 2008 Journal Semin Immunopathol Section Body Doc Link PMC2315691 Disease Relevance 0 Pain Relevance 0

General Comments

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