INT230001

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.53
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neutrophil 2
DEFA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 98 100.00 Very High Very High Very High
cva 6 86.40 High High
Dismenorea 10 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 98 100.00 Very High Very High Very High
Hemorrhage 76 98.12 Very High Very High Very High
Disease 17 94.60 High High
Premature Birth 70 84.16 Quite High
Cancer 51 76.32 Quite High
Infection 15 74.44 Quite High
Stress 4 72.56 Quite High
Genetic Predisposition To Disease 3 72.00 Quite High
Chorioamnionitis 16 71.76 Quite High
Sepsis 3 69.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HMTs methylate specific lysine or arginine residues on nucleosomal histone H3, which in the case of lysine 9 (K9) methylation allows the recruitment of the heterochromatin protein 1 (HP1) stabilizing an inactive condensed chromatin [3].
HP1 Binding (recruitment) of
1) Confidence 0.06 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.26 Pain Relevance 0
Proteomic identification techniques recognized the four protein biomarkers (which comprise the proteomic profile or MR score characteristic for intra-amniotic inflammation) as neutrophil defensin-2, neutrophil defensin-1, calgranulin C and calgranulin A.
neutrophil defensin-1 Binding (recognized) of in neutrophil associated with inflammation
2) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2315798 Disease Relevance 1.64 Pain Relevance 0.34
Proteomic identification techniques recognized the four protein biomarkers (which comprise the proteomic profile or MR score characteristic for intra-amniotic inflammation) as neutrophil defensin-2, neutrophil defensin-1, calgranulin C and calgranulin A.
defensin-2 Binding (recognized) of in neutrophil associated with inflammation
3) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2315798 Disease Relevance 1.63 Pain Relevance 0.34

General Comments

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