INT230018

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc17a5) cytoplasmic membrane-bounded vesicle (Slc17a5) plasma membrane (Slc17a5)
transmembrane transport (Slc17a5) lysosome (Slc17a5)
Slc17a5 (Mus musculus)
Pain Link Frequency Relevance Heat
diclofenac 3 99.66 Very High Very High Very High
cINOD 24 97.70 Very High Very High Very High
Paracetamol 107 96.56 Very High Very High Very High
Osteoarthritis 46 55.04 Quite High
Pain 20 53.60 Quite High
COX-2 inhibitor 8 47.60 Quite Low
Acute pain 2 43.68 Quite Low
Inflammation 25 32.56 Quite Low
Arthritis 21 5.00 Very Low Very Low Very Low
cva 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 3 99.96 Very High Very High Very High
Toxicity 43 99.00 Very High Very High Very High
Hepatotoxicity 10 83.92 Quite High
Drug Induced Neurotoxicity 4 76.48 Quite High
Osteoarthritis 46 55.04 Quite High
Pain 23 53.60 Quite High
INFLAMMATION 27 32.56 Quite Low
Cancer 9 5.16 Low Low
Arthritis 20 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that ALT, AST and BUN may be valid early indicators for monitoring emerging toxicity in patients undergoing treatment with sunitinib and paracetamol.


AST Binding (indicators) of associated with toxicity and paracetamol
1) Confidence 0.21 Published 2010 Journal BMC Pharmacol Section Body Doc Link PMC2965131 Disease Relevance 0.60 Pain Relevance 0.40
However, the incidence rate for lumiracoxib 100 mg o.d. is similar to that reported in the prescribing information for many NSAIDs (1% or less), such as naproxen and ibuprofen [33,34], and less than that observed with diclofenac, which has been associated with ALT and AST abnormalities in 3.2% and 1.8% of patients, respectively [35].
AST Binding (associated) of associated with congenital anomalies, cinod and diclofenac
2) Confidence 0.06 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2322990 Disease Relevance 0.26 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox