INT230096

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.65
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
capillary 1
occludin (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 1 44.16 Quite Low
bradykinin 1 43.48 Quite Low
Inflammatory mediators 1 42.28 Quite Low
cytokine 12 40.40 Quite Low
Inflammation 22 26.88 Quite Low
Central nervous system 9 9.96 Low Low
imagery 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Celiac Disease 58 98.20 Very High Very High Very High
Apoptosis 2 89.92 High High
Hyperplasia 2 88.24 High High
Adhesions 12 83.76 Quite High
Enteropathy 5 82.72 Quite High
Disease 72 81.00 Quite High
Brain Injury 2 52.00 Quite High
Metastasis 76 50.00 Quite Low
Breast Cancer 42 50.00 Quite Low
INFLAMMATION 26 41.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TJs are composed of a complex of belt-like zonula occludin, which is localized close to the lumen of the capillary.
Localization (localized) of occludin in capillary
1) Confidence 0.15 Published 2011 Journal Pathology Research International Section Body Doc Link PMC3021881 Disease Relevance 0.21 Pain Relevance 0
Moreover, the jejunal tight junction structure is morphologically altered in celiac sprue patients [81], and molecular analysis of these junctions has recently revealed that both occludin and E-cadherin fail to localize properly [82].
Localization (localize) of occludin associated with celiac disease
2) Confidence 0.07 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2323203 Disease Relevance 0.44 Pain Relevance 0

General Comments

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