INT230146

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SORL1) Golgi apparatus (APP) extracellular matrix organization (APP)
DNA binding (APP) cytoplasm (APP) cytosol (APP)
APP (Homo sapiens)
SORL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 18 87.24 High High
Alzheimer's Dementia 10 50.00 Quite Low
Stress 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that a similar mechanism may exist whereby APP and OSBP1 both compete for binding to SorL1 or other similar trafficking proteins.
APP Binding (binding) of SorL1
1) Confidence 0.20 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0.08 Pain Relevance 0
These effects were shown to occur via direct interaction between SorL1 and APP.
APP Binding (interaction) of SorL1
2) Confidence 0.19 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0.09 Pain Relevance 0

General Comments

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