INT230168

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Context Info
Confidence 0.78
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (OSBP) transport (OSBP) Golgi apparatus (OSBP)
cytoplasm (OSBP)
OSBP (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 61.16 Quite High
Alzheimer's Dementia 10 50.00 Quite Low
Disease 18 7.36 Low Low
Stress 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Addition of 25OH, which induces translocation of OSBP1 from the ER/cytoplasm to the Golgi, caused APP-Notch2 dimers to translocate from the Golgi to the ER.
Localization (translocation) of OSBP1
1) Confidence 0.78 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0.06 Pain Relevance 0
In addition, 25OH treatment did not alter the overall distribution of APP-GFP expressed alone (Figure 4A), and no noticeable changes in the subcellular localization of BACE1-GFP were observed with OSBP1 co-expression (data not shown).
Localization (observed) of OSBP1
2) Confidence 0.73 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0 Pain Relevance 0

General Comments

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