INT230170

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NOTCH2) cytosol (NOTCH2) nucleoplasm (NOTCH2)
extracellular region (NOTCH2) plasma membrane (NOTCH2) nucleus (NOTCH2)
NOTCH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 54.32 Quite High
Alzheimer's Dementia 5 50.00 Quite Low
Disease 9 22.80 Low Low
Stress 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When OSBP1 was not overexpressed, 25OH had no effect on the localization of the APP-Notch2 dimers, perhaps because basal levels of OSBP1 were not high enough to counteract the effects of 25OH binding to other ORPs or LXRs.
Neg (no) Regulation (effect) of Localization (localization) of Notch2
1) Confidence 0.26 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0.05 Pain Relevance 0

General Comments

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