INT230301

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Context Info
Confidence 0.58
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RAD51) mitochondrion (RAD51) nucleus (RAD51)
cytoplasm (RAD51)
RAD51 (Homo sapiens)
Pain Link Frequency Relevance Heat
IPN 6 7.44 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 12 91.04 High High
Hypersensitivity 6 48.08 Quite Low
Amebiasis 12 42.40 Quite Low
Immunization 6 12.96 Low Low
Malaria 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The EhRAD51 protein is overexpressed in response to DNA damage
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of EhRAD51
1) Confidence 0.58 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0.09 Pain Relevance 0
Our findings showed that EhRAD51 was overexpressed in response to UV-C irradiation, and distributed in both nuclear and cytoplasmic compartments.


Positive_regulation (overexpressed) of Gene_expression (overexpressed) of EhRAD51
2) Confidence 0.58 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0
The expression of rEhRAD51 was induced with 1 mM isopropyl beta-D-thiogalacto pyranoside (IPTG) at 37°C for 3 h.
Positive_regulation (induced) of Gene_expression (expression) of rEhRAD51
3) Confidence 0.58 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0
Increasing amounts of rEhRAD51 (0, 2.5, 5 and 7.5 ?
Positive_regulation (Increasing) of Gene_expression (amounts) of rEhRAD51
4) Confidence 0.42 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0
We also showed that EhRAD51 protein was overexpressed and relocalized in nuclear foci-like structures after DNA damage, and demonstrated that recombinant EhRAD51 function as a recombinase in vitro.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of EhRAD51
5) Confidence 0.39 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0.07 Pain Relevance 0
In response to DNA damage, EhRAD51 protein is overexpressed and relocalized in nuclear foci-like structures.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of EhRAD51
6) Confidence 0.39 Published 2008 Journal BMC Mol Biol Section Abstract Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0

General Comments

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