INT230310

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (XRCC3) nucleus (XRCC3) DNA binding (XRCC3)
cytoplasm (XRCC3)
Anatomy Link Frequency
neck 1
head 1
XRCC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 4 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 99.80 Very High Very High Very High
Cancer 10 98.40 Very High Very High Very High
Shock 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Head & Neck Cancer 2 5.00 Very Low Very Low Very Low
Amebiasis 2 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As in yeast, rad51 paralogs (rad51b, rad51d, xrcc2 and xrcc3) that participate in HR in vertebrates were not found in E. histolytica (Table 1).
Gene_expression (paralogs) of xrcc3
1) Confidence 0.32 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0
To test the possibility that the ICL repair function of ERCC1–XPF functions in concert with HR repair, we used siRNA to knock down the expression of ERCC1, XRCC3 and ERCC1 together with XRCC3 in SQ20B cancer cells of the human head and neck (Figure 9A) and investigated the clonogenic survival following treatments with cisplatin (Figure 9B).
Gene_expression (expression) of XRCC3 in neck associated with targeted disruption and cancer
2) Confidence 0.30 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2770670 Disease Relevance 0.20 Pain Relevance 0
To test the possibility that the ICL repair function of ERCC1–XPF functions in concert with HR repair, we used siRNA to knock down the expression of ERCC1, XRCC3 and ERCC1 together with XRCC3 in SQ20B cancer cells of the human head and neck (Figure 9A) and investigated the clonogenic survival following treatments with cisplatin (Figure 9B).
Gene_expression (expression) of XRCC3 in head associated with targeted disruption and cancer
3) Confidence 0.10 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2770670 Disease Relevance 0.20 Pain Relevance 0

General Comments

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