INT23033

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Context Info
Confidence 0.42
First Reported 1990
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Anatomy Link Frequency
plasma 2
liver 2
Il1a (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 9 92.08 High High
antagonist 1 75.20 Quite High
cytokine 6 75.00 Quite High
anesthesia 2 25.00 Low Low
ketamine 1 25.00 Low Low
cva 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 9 96.72 Very High Very High Very High
Necrosis 2 90.48 High High
Poisoning 2 80.00 Quite High
Hepatotoxicity 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ketoconazole, a potent but transient inhibitor of adrenal steroid hormone biosynthesis, inhibited IL-1 alpha induced increases in plasma corticosterone.
Negative_regulation (inhibited) of Positive_regulation (increases) of IL-1 alpha in plasma
1) Confidence 0.42 Published 1990 Journal Cancer Res. Section Abstract Doc Link 2369744 Disease Relevance 0.41 Pain Relevance 0
Furthermore, neutralization of TNF-alpha delayed the increase in serum IL-1 alpha and liver enzyme levels.
Negative_regulation (delayed) of Positive_regulation (increase) of IL-1 alpha in liver
2) Confidence 0.41 Published 1995 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 7597709 Disease Relevance 0.35 Pain Relevance 0.78

General Comments

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