INT230435

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.11
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DTNBP1) endosome (DTNBP1) endoplasmic reticulum (DTNBP1)
nucleus (DTNBP1) cytoplasm (DTNBP1)
Anatomy Link Frequency
interneurons 1
DTNBP1 (Homo sapiens)
DTNBP1 - G20210A (1)
Pain Link Frequency Relevance Heat
nMDA receptor 1 98.00 Very High Very High Very High
rheumatoid arthritis 1 74.96 Quite High
cerebral cortex 1 72.52 Quite High
cva 3 70.48 Quite High
Inflammation 9 66.08 Quite High
agonist 1 64.40 Quite High
Glutamate receptor 1 64.08 Quite High
Dopamine 8 62.44 Quite High
Glutamate 3 59.52 Quite High
cytokine 1 36.48 Quite Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 43 96.68 Very High Very High Very High
Cognitive Disorder 1 94.96 High High
Schizophrenia 39 94.08 High High
Coagulation Disorder 1 93.64 High High
Disease 13 93.00 High High
Psychosis 7 84.40 Quite High
Thrombosis 12 83.84 Quite High
Abscess 1 82.60 Quite High
Manic Depressive Disorder 3 79.52 Quite High
Embolism 10 75.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tang et al. [14] concluded that decreased dysbindin-1C in the dorsolateral prefrontal cortex may induce NMDA receptor hypofunction in fast-spiking interneurons contributing to the cognitive deficits of schizophrenia.
Negative_regulation (decreased) of dysbindin-1C in interneurons associated with cognitive disorder, nmda receptor and schizophrenia
1) Confidence 0.08 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 1.18 Pain Relevance 0.21
An increased frequency of Factor V Leiden, antithrombin deficiency and the prothrombin (G20210A) gene mutation have not been consistently identified [1].
Negative_regulation (deficiency) of G20210A (G20210A)
2) Confidence 0.01 Published 2008 Journal Thromb J Section Body Doc Link PMC2330027 Disease Relevance 1.93 Pain Relevance 0.11

General Comments

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