INT230494

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.97
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Anatomy Link Frequency
lung 2
microglia 2
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1 92.80 High High
agonist 12 90.32 High High
cytokine 22 89.04 High High
antagonist 12 84.00 Quite High
ketamine 4 64.64 Quite High
anesthesia 2 64.24 Quite High
Central nervous system 38 61.20 Quite High
Inflammation 64 50.00 Quite Low
Cannabinoid receptor 6 50.00 Quite Low
Cannabinoid 6 44.96 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 32 97.84 Very High Very High Very High
Injury 160 96.72 Very High Very High Very High
Burns 222 96.28 Very High Very High Very High
Alzheimer's Dementia 63 93.28 High High
Ileus 4 91.84 High High
Sepsis 8 86.96 High High
Tauopathy 1 81.92 Quite High
Amyloid Plaque 5 67.52 Quite High
Disease 27 57.52 Quite High
INFLAMMATION 80 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TLR4 ligand did not change the bacterial killing activity of peritoneal cells in C3H/HeJ mice
Neg (not) Regulation (change) of TLR4 Binding (ligand) of
1) Confidence 0.45 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2901327 Disease Relevance 0.83 Pain Relevance 0
In another experiment, the lung tissue was harvested for the assay of TLR2, TLR4, and TNF?
Regulation (harvested) of TLR4 Binding (assay) of in lung
2) Confidence 0.45 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2901327 Disease Relevance 1.66 Pain Relevance 0.14
Interestingly, LPS activity did not affect APP processing or A?
Neg (not) Regulation (affect) of LPS Binding (activity) of
3) Confidence 0.05 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2335091 Disease Relevance 0.47 Pain Relevance 0.03
To study the effects of CBR2 activation on cell migration in LPS-stimulated microglia we used the following groups: LPS + JWH015 (0.01–1 ?
Regulation (effects) of LPS Binding (migration) of in microglia
4) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704199 Disease Relevance 0 Pain Relevance 0.13

General Comments

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