INT230577

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Trpv3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 34 100.00 Very High Very High Very High
Calcium channel 2 94.60 High High
TRP channel 60 88.72 High High
alcohol 12 85.52 High High
qutenza 50 70.64 Quite High
Potency 10 48.24 Quite Low
addiction 4 18.72 Low Low
Root ganglion neuron 46 5.00 Very Low Very Low Very Low
imagery 12 5.00 Very Low Very Low Very Low
dorsal root ganglion 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 56 50.00 Quite Low
Pain 8 5.00 Very Low Very Low Very Low
Loss Of Sense Of Smell 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Pruritus 4 5.00 Very Low Very Low Very Low
Bites And Stings 2 5.00 Very Low Very Low Very Low
Tick Infestations 2 5.00 Very Low Very Low Very Low
Contact Dermatitis 2 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Citral is both an activator and inhibitor of TRPV1, TRPV3, TRPM8, and TRPA1, but these opposing actions cannot be attributed to the cis and trans enantiomers.
Negative_regulation (inhibitor) of TRPV3
1) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2346451 Disease Relevance 0 Pain Relevance 0.38
Citral inhibition of agonist-evoked TRPV1, TRPV2, TRPV3, and TRPM8 currents was essentially irreversible (Fig. 2A, D).
Negative_regulation (inhibition) of TRPV3 associated with agonist
2) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2346451 Disease Relevance 0 Pain Relevance 0.08

General Comments

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