INT230585

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) plasma membrane (Trpv1) lipid metabolic process (Trpv1)
Trpv1 (Rattus norvegicus)
Trpm8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 25 99.70 Very High Very High Very High
Root ganglion neuron 23 79.92 Quite High
alcohol 6 74.20 Quite High
agonist 17 68.52 Quite High
TRP channel 30 66.64 Quite High
Pain 4 41.04 Quite Low
imagery 6 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
allodynia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 28 79.60 Quite High
Pain 4 41.04 Quite Low
Loss Of Sense Of Smell 2 40.80 Quite Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Pruritus 2 5.00 Very Low Very Low Very Low
Bites And Stings 1 5.00 Very Low Very Low Very Low
Tick Infestations 1 5.00 Very Low Very Low Very Low
Contact Dermatitis 1 5.00 Very Low Very Low Very Low
Rupture 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TRPV1 activation requires residues in transmembrane segments two through four of the voltage-sensor domain, a region previously implicated in capsaicin activation of TRPV1 and analogous menthol activation of TRPM8.
TRPV1 Positive_regulation (activation) of TRPM8 associated with qutenza
1) Confidence 0.28 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2346451 Disease Relevance 0.15 Pain Relevance 0.36

General Comments

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