INT230658

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.35
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (4930579C15Rik) nucleus (4930579C15Rik) cytoplasm (4930579C15Rik)
Anatomy Link Frequency
bands 1
4930579C15Rik (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 1 63.04 Quite High
Catechol-O-methyltransferase 27 5.00 Very Low Very Low Very Low
Dopamine 15 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
dopamine receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 28 96.92 Very High Very High Very High
Sprains And Strains 101 92.00 High High
Cancer 4 85.56 High High
Heart Disease 4 85.08 High High
Diabetes Mellitus 4 84.48 Quite High
Disease 24 83.36 Quite High
Targeted Disruption 16 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low
Dislocations 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Filtering for eQTL associations occurring within a one megabase window centered around the gene location, we identified 600 cis-eQTLs in adipose.
eQTL Binding (associations) of
1) Confidence 0.17 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2346558 Disease Relevance 0.19 Pain Relevance 0
We then developed a systematic analysis method to relate these patterns of eQTL associations to biological pathways.
eQTL Binding (associations) of
2) Confidence 0.17 Published 2008 Journal PLoS Genetics Section Abstract Doc Link PMC2346558 Disease Relevance 0.44 Pain Relevance 0
We first characterized these eQTL data in the context of cis-eQTL associations, in which a strong association was observed between the expression of a gene and the gene's locally inferred haplotype.
eQTL Binding (associations) of
3) Confidence 0.13 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2346558 Disease Relevance 0.22 Pain Relevance 0
The analysis reported here relies on patterns of eQTLs rather than individual eQTL associations, and any false positives eQTLs resulting from population structure would not be expected to assemble into trans-eQTL bands.
eQTL Binding (associations) of in bands
4) Confidence 0.13 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2346558 Disease Relevance 0.08 Pain Relevance 0
For this reason we closely examined this variant to understand the mechanisms that generate the strong cis eQTL.


eQTL Spec (examined) Binding (generate) of
5) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0.43 Pain Relevance 0.03

General Comments

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