INT230722

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.00
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
heart 1
Hcm (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 16 97.28 Very High Very High Very High
fibrosis 1 80.64 Quite High
Action potential 4 75.08 Quite High
sodium channel 8 58.68 Quite High
Angina 2 57.36 Quite High
addiction 1 33.92 Quite Low
qutenza 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
beta blocker 3 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophic Cardiomyopathy 107 100.00 Very High Very High Very High
Syndrome 58 100.00 Very High Very High Very High
Cardiovascular Disease 5 100.00 Very High Very High Very High
Myocardial Infarction 13 97.72 Very High Very High Very High
Cardiomyopathy 13 96.08 Very High Very High Very High
Recurrence 2 95.24 Very High Very High Very High
Arrhythmia Under Development 27 95.04 Very High Very High Very High
Shock 1 93.72 High High
Hypertrophy 9 83.36 Quite High
Fibrosis 1 80.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because there is limited systematic information about how the increased genetic risk affects the health status of the heart patients with LQTS or HCM, as well as their family members, we investigated the health status in a Norwegian sample of patients at risk of inherited arrhythmia prior to the genetic counselling session.
Regulation (affects) of HCM in heart associated with hypertrophic cardiomyopathy, syndrome and arrhythmia under development
1) Confidence 0.37 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2836315 Disease Relevance 1.02 Pain Relevance 0
In this study we genotyped 245 HCM-patients and 300 healthy controls for 5 polymorphisms in five candidate genes of the angiotensin and serotonin systems.
Regulation (controls) of HCM associated with hypertrophic cardiomyopathy and serotonin
2) Confidence 0.08 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.46 Pain Relevance 0.05
Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiovascular disease affecting one in 500 individuals, and is the most common cause of sudden cardiac death in young athletes [30].
Regulation (affecting) of HCM associated with hypertrophic cardiomyopathy, cardiovascular disease and myocardial infarction
3) Confidence 0.04 Published 2008 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC2363724 Disease Relevance 1.52 Pain Relevance 0.16
For the HCM to be operative in regulation of membrane protein function, ??
Regulation (operative) of HCM
4) Confidence 0.01 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2346573 Disease Relevance 0 Pain Relevance 0

General Comments

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