INT230735

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.22
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (EDNRA) signal transduction (EDNRA) aging (EDNRA)
plasma membrane (EDNRA) signal transducer activity (EDNRA)
EDNRA (Homo sapiens)
Pah (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 18 88.48 High High
fibrosis 6 74.80 Quite High
Inflammation 6 67.84 Quite High
Calcium channel 4 29.20 Quite Low
cva 14 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 324 100.00 Very High Very High Very High
Systemic Sclerosis 32 100.00 Very High Very High Very High
Lower Respiratory Tract Infection 2 81.92 Quite High
Influenza Virus Infection 2 77.52 Quite High
Fibrosis 6 74.80 Quite High
Coronary Heart Disease 10 73.84 Quite High
INFLAMMATION 6 67.84 Quite High
Increased Venous Pressure Under Development 18 67.16 Quite High
Heart Rate Under Development 2 64.48 Quite High
Arrhythmias 2 Under Development 2 57.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preliminary data suggests that ETA selective antagonism may be as effective, at least in idiopathic PAH and scleroderma associated PAH as dual ETA and ETB receptor antagonism (Benedict 2007).


ETA Binding (associated) of PAH associated with pulmonary hypertension and systemic sclerosis
1) Confidence 0.02 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350123 Disease Relevance 1.61 Pain Relevance 0.30
Preliminary data suggests that ETA selective antagonism may be as effective, at least in idiopathic PAH and scleroderma associated PAH as dual ETA and ETB receptor antagonism (Benedict 2007).


ETA Binding (associated) of PAH associated with pulmonary hypertension and systemic sclerosis
2) Confidence 0.02 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350123 Disease Relevance 1.62 Pain Relevance 0.30

General Comments

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