INT230760

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA, Flt1) cell differentiation (Flt1) endosome (Flt1)
Golgi apparatus (Flt1) extracellular space (VEGFA) extracellular region (VEGFA)
Anatomy Link Frequency
retina 1
VEGFA (Homo sapiens)
Flt1 (Mus musculus)
Pain Link Frequency Relevance Heat
diabetic neuropathy 7 84.16 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
peripheral neuropathy 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperglycemia 9 98.52 Very High Very High Very High
Diabetic Macular Edema 9 95.00 High High
Peripheral Neuropathy 9 84.16 Quite High
Diabetes Mellitus 56 81.76 Quite High
Albuminuria 4 65.32 Quite High
Age-related Macular Degeneration 7 52.04 Quite High
Wound Healing 1 50.48 Quite High
Ocular Toxicity (including Many Sub-types) 13 19.80 Low Low
Renal Disease 14 5.00 Very Low Very Low Very Low
Neuropathic Pain 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VEGF mediates its effects on the retina through the receptor tyrosine kinases VEGFR-1 and VEGFR-2 (Shen et al 1993; Ferrara 2004).
VEGF Positive_regulation (mediates) of VEGFR-1 in retina
1) Confidence 0.03 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350125 Disease Relevance 0.96 Pain Relevance 0.12

General Comments

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