INT230779

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.78
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MCRS1) protein modification process (MCRS1) nucleolus (MCRS1)
nucleus (MCRS1) cytoplasm (MCRS1)
Anatomy Link Frequency
cerebrospinal fluid 2
MCRS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 307 100.00 Very High Very High Very High
alcohol 2 79.08 Quite High
Inflammation 16 75.48 Quite High
cytokine 24 61.52 Quite High
ischemia 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 274 100.00 Very High Very High Very High
Brain Injury 148 97.32 Very High Very High Very High
Brain Hemorrhage 2 95.28 Very High Very High Very High
Death 9 93.44 High High
Coma 8 93.12 High High
Dyspnea 1 91.96 High High
Intracranial Hypertension 8 88.76 High High
Hemorrhage 7 85.32 High High
Injury 95 83.68 Quite High
Aneurism 21 80.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although no prophylactic treatment is currently available to prevent elevated ICP, neurointensivists and neurosurgeons often use sedatives, mannitol, hypertonic saline, cerebrospinal fluid drainage, decompressive craniectomy, and/or barbiturate-induced coma to manage this condition.
Negative_regulation (prevent) of Positive_regulation (elevated) of ICP in cerebrospinal fluid associated with cva and coma
1) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2853529 Disease Relevance 1.58 Pain Relevance 0.46
Elevated ICP was defined as a ?
Negative_regulation (defined) of Positive_regulation (Elevated) of ICP associated with cva
2) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2853529 Disease Relevance 1.38 Pain Relevance 0.35
Unilateral or bilateral decompressive craniotomy (DC) showed additional benefits for all these patients reducing ICP and increasing CPP.
Negative_regulation (reducing) of Positive_regulation (increasing) of ICP associated with cva
3) Confidence 0.02 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350130 Disease Relevance 0.83 Pain Relevance 0.11

General Comments

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