INT230803

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2011
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.89
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ace) peptidase activity (Ace) extracellular space (Ace)
extracellular region (Ace) plasma membrane (Ace)
Anatomy Link Frequency
coronary artery 2
Ace (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 61 98.48 Very High Very High Very High
Kinase C 6 88.88 High High
metalloproteinase 41 82.56 Quite High
Catecholamine 1 72.00 Quite High
Pseudotolerance 6 70.52 Quite High
Potency 6 56.28 Quite High
bradykinin 4 19.40 Low Low
ischemia 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 42 99.56 Very High Very High Very High
Disease 47 97.68 Very High Very High Very High
Stress 28 96.44 Very High Very High Very High
Systolic Heart Failure 1 89.28 High High
Metabolic Syndrome 12 88.28 High High
Diabetes Mellitus 97 87.36 High High
Myocardial Infarction 19 87.36 High High
Impaired Glucose Tolerance 5 85.80 High High
Left Ventricular Dysfunction 5 84.24 Quite High
Cv Unclassified Under Development 16 70.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical trials of ACE inhibitors in stable coronary artery disease
Regulation (trials) of Negative_regulation (inhibitors) of ACE in coronary artery associated with coronary artery disease
1) Confidence 0.39 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350139 Disease Relevance 1.49 Pain Relevance 0.09
The question arises, therefore, as to whether the effect of ACE inhibitors on A?
Spec (whether) Regulation (effect) of Spec (whether) Negative_regulation (inhibitors) of ACE
2) Confidence 0.12 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989646 Disease Relevance 0.31 Pain Relevance 0.12
In contrast, there is a limited number of studies reporting on lack of effect of ACE inhibitors and AT1-receptor blockers on nitrate tolerance [54–56] and nitrate-induced oxidative stress [57].
Regulation (effect) of Negative_regulation (inhibitors) of ACE associated with stress and tolerance
3) Confidence 0.03 Published 2010 Journal Experimental Diabetes Research Section Body Doc Link PMC3014692 Disease Relevance 0.10 Pain Relevance 0.60

General Comments

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