INT230827

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (COBRA1) nucleolus (COBRA1) nucleus (COBRA1)
cytoplasm (COBRA1)
COBRA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 82 99.62 Very High Very High Very High
methotrexate 5 98.52 Very High Very High Very High
corticosteroid 8 80.92 Quite High
Adalimumab 3 45.28 Quite Low
Etanercept 3 43.00 Quite Low
Infliximab 12 32.48 Quite Low
antagonist 1 17.56 Low Low
cytokine 1 12.16 Low Low
Inflammation 16 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 84 99.62 Very High Very High Very High
Disorder Of Lipid Metabolism 67 96.88 Very High Very High Very High
Disease 34 92.04 High High
Cardiovascular Disease 16 40.32 Quite Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Dyslipidemia /

Combined Dyslipidemia

13 5.00 Very Low Very Low Very Low
Atherosclerosis 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Total and HDL cholesterol levels were determined in stored samples from a previously conducted, 56-week multicenter trial among patients with early RA investigating the value of intensive combination therapy (COBRA); the combination of sulfasalazine, methotrexate (stopped at 40 weeks) and prednisolone (initially 60 mg/day, tapered in 6 weekly steps to 7.5 mg/day and stopped after 28 weeks) was compared to sulfasalazine alone (Boers et al 1997).
Spec (investigating) Regulation (value) of COBRA associated with rheumatoid arthritis, methotrexate and disorder of lipid metabolism
1) Confidence 0.02 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350142 Disease Relevance 1.08 Pain Relevance 0.35

General Comments

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