INT230855

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NOS1) extracellular space (KNG1) oxidoreductase activity (NOS1)
extracellular region (KNG1) cytoskeleton (NOS1) plasma membrane (KNG1)
Anatomy Link Frequency
endothelial cell 1
KNG1 (Homo sapiens)
NOS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 7 100.00 Very High Very High Very High
cytokine 14 66.92 Quite High
Inflammation 44 53.92 Quite High
tolerance 21 5.00 Very Low Very Low Very Low
Kinase C 18 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 56 98.12 Very High Very High Very High
Adhesions 34 68.72 Quite High
INFLAMMATION 44 62.88 Quite High
Hemorrhage 3 62.16 Quite High
Stress 53 58.48 Quite High
Thrombosis 5 54.40 Quite High
Vasculitis 8 53.92 Quite High
Apoptosis 90 50.00 Quite Low
Diabetes Mellitus 285 43.24 Quite Low
Nicotine Addiction 5 42.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NOS also are regulated by local concentrations of bradykinin (Busse et al 1993).
bradykinin Regulation (regulated) of NOS associated with bradykinin
1) Confidence 0.03 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350146 Disease Relevance 0.41 Pain Relevance 0.13
NOS is regulated by bradykinin, which acts with b2 receptors on the endothelial cell surface membrane, increasing the production of NO via NOS activation.
bradykinin Regulation (regulated) of NOS in endothelial cell associated with bradykinin
2) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2903979 Disease Relevance 0.53 Pain Relevance 0.19

General Comments

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