INT230857

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.18
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HSP90AA1, NOS1) cytosol (HSP90AA1, NOS1) unfolded protein binding (HSP90AA1)
small molecule metabolic process (HSP90AA1) intracellular (HSP90AA1) response to stress (HSP90AA1)
HSP90AA1 (Homo sapiens)
NOS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 15 91.76 High High
Kinase C 8 82.24 Quite High
alcohol 1 39.28 Quite Low
tolerance 20 21.92 Low Low
bradykinin 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 18 96.20 Very High Very High Very High
Diabetes Mellitus 202 95.28 Very High Very High Very High
Hyperglycemia 24 94.16 High High
INFLAMMATION 15 91.76 High High
Adhesions 18 90.72 High High
Increased Venous Pressure Under Development 37 77.48 Quite High
Stress 22 69.12 Quite High
Diabetic Angiopathy 4 64.72 Quite High
Obesity 13 43.48 Quite Low
Nicotine Addiction 3 38.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunoprecipitation studies revealed that glucose induces loss of NO via a calpain-dependent decrease in the association of hsp90 with endothelial NOS.
Negative_regulation (decrease) of hsp90 Binding (association) of NOS
1) Confidence 0.05 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350146 Disease Relevance 1.18 Pain Relevance 0.09

General Comments

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