INT230875

Context Info Confidence 0.11 First Reported 2007 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.20 Pain Relevance 0.06

extracellular region (C9) plasma membrane (C9)

Anatomy Link Frequency heart 1 C9 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 4 68.40 Inflammation 37 54.60 ischemia 4 5.00 Morphine 3 5.00 Inflammatory stimuli 3 5.00 anesthesia 2 5.00 Inflammatory response 2 5.00 alcohol 2 5.00 cva 2 5.00 imagery 2 5.00

Disease Link Frequency Relevance Heat Death 37 100.00 Necrosis 12 97.24 Overdose 4 93.84 Stress 28 91.20 Apoptosis 30 89.12 INFLAMMATION 33 54.60 Myositis 42 50.00 Myocardial Infarction 13 5.00 Disease 7 5.00 Anaphylaxis 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

No fiber showed positive immunoreactivity for ubiquitin, a marker of proteasome overload and autophagic death [29], and for serum complement protein C9, whose intracellular localization is indicative for the presence of necrosis [29].

C9 Neg (No) Binding (immunoreactivity) of associated with necrosis and death

1) Confidence 0.11 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888201 Disease Relevance 0.44 Pain Relevance 0.03

Four heart sections of each case were then investigated for binding of C9 antibody to the sarcolemma.

C9 Binding (binding) of in heart

2) Confidence 0.05 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350147 Disease Relevance 0.76 Pain Relevance 0.03

General Comments

This test has worked.